Drug Metabolism and Pharmacokinetics Scientist

Application deadline: 31-Jan-2026 
Location: Ballerup 2750, , Denmark 
Contract type: Permanent 
Job ID: 4092 

Do you want to play a key role in shaping the future of dermatology and drug development? Would you thrive acting with independence while partnering closely with world-class scientists? Are you looking for an opportunity to make a real impact on projects that reach far beyond the skin?

Join us in creating a future legacy in medical dermatology 

 At LEO Pharma, our mission transcends the conventional. We're on an ambitious path to become the leaders in medical dermatology worldwide. If you're ready to make a difference, this role is your gateway to a world of opportunities!

In the Science department, we share a “challenge accepted” mindset and are guided by our winning behaviours of simplification, collaboration, and accountability, to achieve our goals.

We welcome applications for this position from  Denmark, and Poland.

Your role

As our new DMPK Scientist, you will lead and execute investigations into ADME properties for early and late-stage projects. You will be the contact point for PK studies, coordinating with CRO partners, and delivering insights that directly support dose setting, dermal formulation, and global product team decisions.

You will work closely with multidisciplinary scientific teams, providing strategic input and execution, bridging pharmacokinetics modelling and translational sciences.

Your key tasks:

• Design and execute studies externally to optimise ADME properties in topical and systemic drug products.
• Apply and interpret PK/PD modelling tools (e.g., Phoenix, R) to inform exposure–effect relationships.
• Provide holistic DMPK support to development teams across absorption studies, metabolism profiling, and drug-drug interaction understanding.
• Coordinate and manage studies with external CROs in partnership with internal outsourcing functions.
• Shape skin PK strategies for profiling compounds in alignment with basic pharmacology and therapeutic goals.

Additional responsibilities include translational dose predictions, integration with toxicology and formulation teams, and close collaboration with innovation partners. Experience in dermal PK assessment with PK/PD models is considered an advantage.

Your qualifications

We are seeking a scientist with strong technical and scientific skills in pharmacokinetics and drug metabolism, paired with the ability to act independently while engaging closely with internal and external stakeholders.

Key requirements:

• PhD in biology, biochemistry, biomedicine, or other related field.
• Significant pharma/biotech research experience — preferably in ADME, DMPK, and PK/PD.
• Strong understanding of relevant animal models for PK/PD.
• Solid knowledge of drug development stages and processes.
• Preferably, experience in dermal PK measurements.

On a personal level, you are you are a clear communicator who can connect with both scientific and non-scientific audiences, building  trusted collaborations across disciplines. You make decisions with sound judgment, guided by science, data, and experience. You work in an organised and proactive way, prioritising effectively to keep projects on track and moving forward.

Your new team

You will join a small, diverse team of six people in the Science Department , working alongside experienced PK experts, scientists, and external CRO partners. You’ll have the freedom to act independently, bring your expertise to key studies, and collaborate in a supportive environment where your contributions directly influence early drug development across dermatology, immunology, and oncology.

Beyond the skin

Join LEO Pharma, a global leader in medical dermatology, as we go beyond the skin to make a lasting impact. Our innovative approach sets us apart. We are dedicated to leaving a legacy that positively impacts patients, colleagues, and our planet.

At LEO Pharma, we believe in the power of individuals to drive change. Our flat organizational structure empowers you to make a visible impact and offers versatile roles for professional growth. We value diversity and welcome applications from all qualified candidates, recognizing that our different perspectives, backgrounds, and attitudes enable us to make the best decisions. Join our passionate team at LEO Pharma and be yourself as we work together to make a difference.

For certain positions, LEO Pharma might complete a background check conducted by a third party.

Join us on our journey Beyond the Skin. Apply today!

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